Karen A. Kaine, age 72 of Charlestown, RI formerly of Oxford passed away on June 23, 2021 at her home. Daughter of the late Harold and Nancy Salamone Fisher.  She was the beloved mother of Jeffrey B. Kaine of Charlestown, RI.  Stephen L. (Donna) Kaine of Stratford and the late Jason D. Kaine  and wife of  Larry Kaine of Charlestown, RI.  She was a loving grandmother to four grandsons, Lucas Kaine of Burlington, VT, Pvt Liam Kaine of Ft. Bragg, NC, Brody and Callen Kaine of Stratford. Also survived by daughter in law, Joyce Kaine of Oxford and several cousins. Karen was a real estate broker and the retired co-owner Wallander Real Estate in Charlestown.   Visiting hours will be held on Sunday June 27, 2021 from 2:00 p.m. to 6:00 p.m. in the Dennis & D'Arcy – Abriola & Kelemen Funeral Home, 2611 Main St. Stratford.  A Mass of Christian  Burial will be celebrated on Monday June 28, 2021 at 10:30 a.m. in James Church, Stratford. Burial will follow in Lawncroft Cemetery. Fairfield.